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29 Nov 2024

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Thematic Research Group

Thematic Research Group (TRG) is a focused, productive, and impactful research group within a faculty dedicated to strengthening research capacity and improving the quality of education, research, and community service.

Enhance academic reputation

Boosts university’s prestige through excellence in research, teaching, and community engagement

attract international students & lecturers

Draws global talent by offering diverse, inclusive, and high-quality educational opportunities

strengthen collaboration partners

Fosters robust partnerships through shared research, resources, and innovative projects

Prof. Dr. Ir. Jamaluddin Jompa, M.Sc
Rector of Hasanuddin University

About TRG

strengthen the research capacity of each faculty

At Universitas Hasanuddin (UNHAS), a Thematic Research Group (TRG) is a focused, productive, and impactful research group within a faculty dedicated to strengthening research capacity and improving the quality of education, research, and community service. TRGs are led by a leader and are characterized by their focus on specific research themes, active engagement in research activities, and contributions to the advancement of knowledge, innovation, and societal problem-solving.

The TRG will be led by a leader and integrated with several strategic programs, for example:

Research Group

A team of experts collaborating to advance knowledge and solve complex scientific problems.

Agro Complex

Integrates agricultural sciences to enhance sustainable farming, food production, and rural development

Social Science

Studies human behavior, societies, and social relationships to understand and improve societal dynamics

Science and Engineering

Advances technology and scientific knowledge through innovative research and practical applications

8. Green Hydrogen Energy Technology Research Group
27. AI Robotics Research Group
40. Natural Fiber Technology Research Group

Medical and Health Science

Focuses on improving health outcomes through medical research, clinical practice, and public health initiatives

Vocational

Provides practical skills and training for specific trades and professions to enhance employability

Multidisciplinary

Combines multiple academic disciplines to address complex problems with comprehensive, integrated approaches

latest research

the research we have done

Our research has significantly advanced knowledge in various fields, contributing to innovative solutions and groundbreaking discoveries

This study examines the characteristics, industrial impacts, and settlement arrangement directions for the self-help settlements located within a two-kilometer radius of the largest cement industrial area in Eastern Indonesia, situated in Biringere Village, Pangkep Regency. The research objectives are threefold: (1) to identify the socio-spatial characteristics of the settlements and communities; (2) to assess the industrial impacts on these communities; and (3) to propose settlement arrangement directions for mitigating adverse effects. Data were collected through interviews, field surveys, questionnaires, and agency consultations. Analytical methods employed include qualitative and quantitative descriptive analysis, spatial analysis, and cross-tabulation. The findings reveal: (1) building orientations predominantly facing roads, with permanent construction dominating (37%), family/private land ownership, and private home ownership; a significant portion of dwellings are located within one kilometer of the industry, and settlement expansion occurred at a rate of 1.41% between 2013 and 2023; (2) social interaction is generally established (69%), with 49% of residents experiencing employment opportunities and income increases, while 51% do not; PT. Semen Tonasa provides infrastructural support, including schools, hospitals, and mosques. However, residents report dust pollution, ground vibrations, noise, and health issues such as coughing and skin irritation; and (3) recommended settlement arrangement directions include the development of an enhanced Green Belt with recreational facilities and the empowerment of Micro, Small, and Medium Enterprises (MSMEs) to reduce unemployment.

The aim of this study is to understand the pathomechanism of this disease and to map the interaction and transmission patterns between cattle and humans using a One Health approach. This research aligns with the Strategic Plan and Research Roadmap of Hasanuddin University (Unhas), particularly under the medical complex cluster which focuses on addressing infectious diseases as one of Unhas’ flagship research areas for the 2020–2024 period. In 2024, this research began with the identification of Mycobacterium tuberculosis in cow’s milk in Enrekang Regency, revealing a positivity rate of over 40%. However, the presence of Mycobacterium bovis, the primary causative agent of bTB, has yet to be confirmed. Thus, the 2025 research will focus on the isolation and identification of M. bovis using commercial diagnostic kits (Interferon-Gamma Release Assay), acid-fast bacilli staining (Ziehl-Neelsen method), DNA extraction, and molecular detection through Polymerase Chain Reaction (PCR). Additionally, surveillance and mapping of bTB transmission potential in Enrekang Regency will be conducted. The research will also examine the production performance and health of dairy cattle, as well as the quality of milk and dairy products, to ensure local food safety. One key health aspect to be studied is the potential of M. bovis to infect the mammary glands, which could significantly impact farmers due to prolonged milk contamination rendering it unsuitable for consumption. The specific objectives are to provide awareness and education to farmers and the general public about the zoonotic potential of bTB and to propose mitigation efforts for disease transmission from animals to humans, while also improving the quality and safety of milk and its derivatives. The research findings on the epidemiology and characteristics of bTB in dairy cattle are expected to contribute significantly to scientific knowledge and form the basis for the development of advanced diagnostic tools and treatments in the future.

The aim of this study is to understand the pathomechanism of this disease and to map the interaction and transmission patterns between cattle and humans using a One Health approach. This research aligns with the Strategic Plan and Research Roadmap of Hasanuddin University (Unhas), particularly under the medical complex cluster which focuses on addressing infectious diseases as one of Unhas’ flagship research areas for the 2020–2024 period. In 2024, this research began with the identification of Mycobacterium tuberculosis in cow’s milk in Enrekang Regency, revealing a positivity rate of over 40%. However, the presence of Mycobacterium bovis, the primary causative agent of bTB, has yet to be confirmed. Thus, the 2025 research will focus on the isolation and identification of M. bovis using commercial diagnostic kits (Interferon-Gamma Release Assay), acid-fast bacilli staining (Ziehl-Neelsen method), DNA extraction, and molecular detection through Polymerase Chain Reaction (PCR). Additionally, surveillance and mapping of bTB transmission potential in Enrekang Regency will be conducted. The research will also examine the production performance and health of dairy cattle, as well as the quality of milk and dairy products, to ensure local food safety. One key health aspect to be studied is the potential of M. bovis to infect the mammary glands, which could significantly impact farmers due to prolonged milk contamination rendering it unsuitable for consumption. The specific objectives are to provide awareness and education to farmers and the general public about the zoonotic potential of bTB and to propose mitigation efforts for disease transmission from animals to humans, while also improving the quality and safety of milk and its derivatives. The research findings on the epidemiology and characteristics of bTB in dairy cattle are expected to contribute significantly to scientific knowledge and form the basis for the development of advanced diagnostic tools and treatments in the future.

This study aims to investigate the potential of passion fruit (Passiflora edulis) extract—an endemic fruit from Malino, Gowa Regency—in enhancing the reproductive performance of livestock males through an experimental study using mice (Mus musculus). The focus is on spermatogenesis, testicular histological structure, sperm quality, and testosterone hormone levels. In the long term, this research is expected to contribute to the development of natural-based supplements to sustainably improve livestock male fertility, aligning with Hasanuddin University’s Strategic Plan (Renstra) in supporting innovation based on local biodiversity and strengthening research in the field of animal reproduction. The specific objectives of this study include determining the optimal dose of passion fruit extract, identifying histological changes in the testes, evaluating sperm quality, assessing testosterone levels, and producing SINTA-indexed publications and national proceedings. The methodology consists of an experimental and descriptive design, with mice divided into four treatment groups: a control group and three treatment groups receiving extract doses of 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW. The extract is prepared using the maceration method with 70% ethanol, followed by evaporation to obtain a thick extract, which is administered orally for 28 days. The observed parameters include sperm quality analysis, testosterone hormone levels using the ELISA method, and observations of spermatogenesis and testicular histology. Data will be analyzed descriptively and through one-way ANOVA to assess the significance of differences between groups. This research supports the roadmap of Animal Production and Health Research, focusing on the development of environmentally friendly reproductive technologies based on local resources.

This study investigates the interplay between coastal economic activities, disaster vulnerability, and infrastructure needs in Ujung Lero Hamlet, Pinrang Regency, South Sulawesi. The coastal area supports diverse economic activities, including salt farming, aquaculture, and fishing, but faces significant risks from coastal abrasion, impacting local economic development. The research objectives were to: (1) analyze settlement characteristics and coastal disaster threats to local economic conditions; (2) assess infrastructure needs for remote coastal settlements; (3) examine community participation and socio-economic resilience against disaster risks; and (4) conceptualize infrastructure development for coastal settlement mitigation to support a service-based economy. Data were collected through surveys, observations, and interviews with fishing groups, and analyzed using descriptive comparative methods, SPSS, scoring, and SWOT analysis. Results indicate that coastal housing in Lero Village is disaster-prone, and infrastructure supporting local service and economic activities is inadequate, with a 46% overall condition rating. Specifically, fish drying, fish auction sites, ship repair, ice, and fuel procurement facilities are rated poorly, while road networks are rated favorably. An aggressive maintenance strategy, focusing on infrastructure optimization and development using a Weakness-Opportunity (W-O) approach, is recommended. The proposed development concept emphasizes livable settlements with wind-resistant housing, community-based disaster response groups, and human resource development to support tourism and economic diversification.

This study aims to investigate the therapeutic potential of Lannea coromandelica bark extract, a traditional remedy used by communities in South Sulawesi for wound healing, abdominal pain, and cough relief. The research focuses on identifying the bioactive compounds responsible for its anti-inflammatory and wound-healing properties and evaluating their efficacy through a combination of in vitro, in vivo, and in silico approaches. By integrating these methods, the study seeks to uncover the molecular mechanisms underlying the extract's therapeutic effects, particularly its interaction with key protein targets such as COX-2, TNF-α, and VEGF, which are critical in inflammation and wound healing processes.
The findings from this research are expected to provide a scientific foundation for the development of phytopharmaceutical products derived from Lannea coromandelica bark, leveraging its traditional use and potential as a natural therapeutic agent. The study also aims to contribute to the broader understanding of plant-based medicines and their applications in modern healthcare.
This research will employ a multidisciplinary methodology, including extraction and identification of bioactive compounds, biological activity assays, and computational simulations to predict molecular interactions. The results will be analyzed to determine the extract's effectiveness in reducing inflammation and promoting wound healing, with the ultimate goal of supporting the development of evidence-based herbal medicines.

why TRG

Foster innovation, drive collaboration

Join a research group to collaborate, innovate, and contribute to cutting-edge discoveries that shape the future of science and technology

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