This study examines the characteristics, industrial impacts, and settlement arrangement directions for the self-help settlements located within a two-kilometer radius of the largest cement industrial area in Eastern Indonesia, situated in Biringere Village, Pangkep Regency. The research objectives are threefold: (1) to identify the socio-spatial characteristics of the settlements and communities; (2) to assess the industrial impacts on these communities; and (3) to propose settlement arrangement directions for mitigating adverse effects. Data were collected through interviews, field surveys, questionnaires, and agency consultations. Analytical methods employed include qualitative and quantitative descriptive analysis, spatial analysis, and cross-tabulation. The findings reveal: (1) building orientations predominantly facing roads, with permanent construction dominating (37%), family/private land ownership, and private home ownership; a significant portion of dwellings are located within one kilometer of the industry, and settlement expansion occurred at a rate of 1.41% between 2013 and 2023; (2) social interaction is generally established (69%), with 49% of residents experiencing employment opportunities and income increases, while 51% do not; PT. Semen Tonasa provides infrastructural support, including schools, hospitals, and mosques. However, residents report dust pollution, ground vibrations, noise, and health issues such as coughing and skin irritation; and (3) recommended settlement arrangement directions include the development of an enhanced Green Belt with recreational facilities and the empowerment of Micro, Small, and Medium Enterprises (MSMEs) to reduce unemployment.

The aim of this study is to understand the pathomechanism of this disease and to map the interaction and transmission patterns between cattle and humans using a One Health approach. This research aligns with the Strategic Plan and Research Roadmap of Hasanuddin University (Unhas), particularly under the medical complex cluster which focuses on addressing infectious diseases as one of Unhas’ flagship research areas for the 2020–2024 period. In 2024, this research began with the identification of Mycobacterium tuberculosis in cow’s milk in Enrekang Regency, revealing a positivity rate of over 40%. However, the presence of Mycobacterium bovis, the primary causative agent of bTB, has yet to be confirmed. Thus, the 2025 research will focus on the isolation and identification of M. bovis using commercial diagnostic kits (Interferon-Gamma Release Assay), acid-fast bacilli staining (Ziehl-Neelsen method), DNA extraction, and molecular detection through Polymerase Chain Reaction (PCR). Additionally, surveillance and mapping of bTB transmission potential in Enrekang Regency will be conducted. The research will also examine the production performance and health of dairy cattle, as well as the quality of milk and dairy products, to ensure local food safety. One key health aspect to be studied is the potential of M. bovis to infect the mammary glands, which could significantly impact farmers due to prolonged milk contamination rendering it unsuitable for consumption. The specific objectives are to provide awareness and education to farmers and the general public about the zoonotic potential of bTB and to propose mitigation efforts for disease transmission from animals to humans, while also improving the quality and safety of milk and its derivatives. The research findings on the epidemiology and characteristics of bTB in dairy cattle are expected to contribute significantly to scientific knowledge and form the basis for the development of advanced diagnostic tools and treatments in the future.

The aim of this study is to understand the pathomechanism of this disease and to map the interaction and transmission patterns between cattle and humans using a One Health approach. This research aligns with the Strategic Plan and Research Roadmap of Hasanuddin University (Unhas), particularly under the medical complex cluster which focuses on addressing infectious diseases as one of Unhas’ flagship research areas for the 2020–2024 period. In 2024, this research began with the identification of Mycobacterium tuberculosis in cow’s milk in Enrekang Regency, revealing a positivity rate of over 40%. However, the presence of Mycobacterium bovis, the primary causative agent of bTB, has yet to be confirmed. Thus, the 2025 research will focus on the isolation and identification of M. bovis using commercial diagnostic kits (Interferon-Gamma Release Assay), acid-fast bacilli staining (Ziehl-Neelsen method), DNA extraction, and molecular detection through Polymerase Chain Reaction (PCR). Additionally, surveillance and mapping of bTB transmission potential in Enrekang Regency will be conducted. The research will also examine the production performance and health of dairy cattle, as well as the quality of milk and dairy products, to ensure local food safety. One key health aspect to be studied is the potential of M. bovis to infect the mammary glands, which could significantly impact farmers due to prolonged milk contamination rendering it unsuitable for consumption. The specific objectives are to provide awareness and education to farmers and the general public about the zoonotic potential of bTB and to propose mitigation efforts for disease transmission from animals to humans, while also improving the quality and safety of milk and its derivatives. The research findings on the epidemiology and characteristics of bTB in dairy cattle are expected to contribute significantly to scientific knowledge and form the basis for the development of advanced diagnostic tools and treatments in the future.

This study aims to investigate the potential of passion fruit (Passiflora edulis) extract—an endemic fruit from Malino, Gowa Regency—in enhancing the reproductive performance of livestock males through an experimental study using mice (Mus musculus). The focus is on spermatogenesis, testicular histological structure, sperm quality, and testosterone hormone levels. In the long term, this research is expected to contribute to the development of natural-based supplements to sustainably improve livestock male fertility, aligning with Hasanuddin University’s Strategic Plan (Renstra) in supporting innovation based on local biodiversity and strengthening research in the field of animal reproduction. The specific objectives of this study include determining the optimal dose of passion fruit extract, identifying histological changes in the testes, evaluating sperm quality, assessing testosterone levels, and producing SINTA-indexed publications and national proceedings. The methodology consists of an experimental and descriptive design, with mice divided into four treatment groups: a control group and three treatment groups receiving extract doses of 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW. The extract is prepared using the maceration method with 70% ethanol, followed by evaporation to obtain a thick extract, which is administered orally for 28 days. The observed parameters include sperm quality analysis, testosterone hormone levels using the ELISA method, and observations of spermatogenesis and testicular histology. Data will be analyzed descriptively and through one-way ANOVA to assess the significance of differences between groups. This research supports the roadmap of Animal Production and Health Research, focusing on the development of environmentally friendly reproductive technologies based on local resources.